Program Operations Manual System (POMS)
TN 61 (10-23)
DI 23022.105 Anaplastic Adrenal Cancer - Adult with Distant Metastases or Inoperable, Unresectable
or Recurrent
COMPASSIONATE ALLOWANCES INFORMATION
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ANAPLASTIC ADRENAL CANCER -
ADULT WITH DISTANT
METASTASES OR INOPERABLE, UNRESECTABLE OR RECURRENT
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ALTERNATE NAMES
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DESCRIPTION
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Anaplastic Adrenal Cancer is a sub-type of adrenal cancer, which shows virtually no cellular differentiation.
It is not associated with overproduction of hormones as is seen in other types of
adrenal carcinomas. Abdominal pain is a presenting symptom.
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DIAGNOSTIC TESTING, PHYSICAL FINDINGS, AND ICD-9-CM/ICD-10-CM CODING
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Diagnostic testing: Anaplastic Adrenal Cancer is diagnosed by CT or MRI scans. An adrenal gland biopsy
is definitive.
Physical findings: Individuals with Anaplastic Adrenal Cancer generally present with:
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Abdominal pain and tenderness;
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Abdominal pain, fullness, and tenderness; and
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An abdominal mass that is hard and non-movable.
ICD-9: 194.0
ICD-10: C79.70
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PROGRESSION
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Median survival for anaplastic adrenal cancer is 5 months as compared with a median
survival of 40 months for differentiated adrenal cancers.
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TREATMENT
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Radical surgical excision is the treatment for individuals with localized malignancies
and remains the only method by which long-term disease-free survival may be achieved.
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SUGGESTED PROGRAMMATIC ASSESSMENT*
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Suggested MER for Evaluation:
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Clinical history and examination that describes the diagnostic features of the impairment;
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Imaging studies of CT scan or MRI will suggest a diagnosis; and
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An adrenal gland biopsy is definitive.
“Inoperable” refers to a physician's opinion that surgery would not be beneficial
based on a review of imaging studies, laboratory results, and physical examination
findings.
“Unresectable” cancer is established when the operative report indicates that the
cancer is not completely removed or the pathology report notes that the surgical specimen
has positive margins.
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Suggested Listings for Evaluation:
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DETERMINATION
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LISTINGS
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REMARKS
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Meets
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13.21
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Anaplastic carcinoma of the adrenal gland is evaluated under 13.21 A if inoperable,
unresectable, or recurrent. Anaplastic cancer of the adrenal glands with metastases
is evaluated under 13.21 B.
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Equals
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* Adjudicators may, at their discretion, use the Medical Evidence of Record or the
listings suggested to evaluate the claim. However, the decision to allow or deny the
claim rests with the adjudicator.
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To Link to this section - Use this URL: http://policy.ssa.gov/poms.nsf/lnx/0423022105
| DI 23022.105 - Anaplastic Adrenal Cancer - Adult with Distant Metastases or Inoperable, Unresectable or Recurrent - 10/05/2023
Batch run: 10/05/2023
Rev:10/05/2023 |