Program Operations Manual System (POMS)
TN 88 (12-25)
DI 23022.300 Small Cell Cancer of the Large Intestine
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COMPASSIONATE ALLOWANCES INFORMATION
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SMALL CELL CANCER OF THE LARGE INTESTINE
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ALTERNATE NAMES
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Cancer of the Colon; Colorectal Small Cell Cancer; Small Cell Carcinoma of the Large
Intestine
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DESCRIPTION
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Small
cell
cancer
of the
large
intestine is an aggressive (fast-growing) cancer that forms in tissues of the intestine and
can spread to other parts of the body. The cancer cells look small and oval-shaped
when looked at under a microscope. Small cell cancer of the large intestine represents
.2-.8% of all colorectal malignancies.
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DIAGNOSTIC TESTING, PHYSICAL FINDINGS, AND ICD-9-CM/ICD-10-CM CODING
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Diagnostic testing: The diagnosis of small cell cancer of the large intestine is confirmed by pathology
and the use of immunohistochemistry. Specific staining for CD56, pancytokeratin, LMWK,
CK 7, and 19 are usually positive in small cell malignancies.
Early diagnosis depends on:
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-
-
-
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•
Computed tomography (CT) scan; and
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Physical findings: General symptoms may include:
ICD-9: 209.0
ICD-10: C7A.019
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PROGRESSION
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Survival rates are poor, usually less than 2 years.
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TREATMENT
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Treatment for small cell cancer of the large intestine is the use of combined chemotherapy
and radiotherapy as is used in small cell cancer of the lung.
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SUGGESTED PROGRAMMATIC
ASSESSMENT*
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Suggested MER for Evaluation: The diagnosis of small cell cancer of the large intestine is a pathologic diagnosis
which would be confirmed by a pathology report of colonoscopy specimen.
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Suggested Listings for Evaluation:
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DETERMINATION
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LISTING
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REMARKS
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Meets
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13.18
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Equals
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* Adjudicators may, at their discretion, use the Medical Evidence of Record or the
listings suggested to evaluate the claim. However, the decision to allow or deny the
claim rests with the adjudicator.
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