1. These listings are only common examples of hematological disorders that we consider
severe enough to result in marked and severe functional limitations. If your disorder
does not meet the criteria of any of these listings, we must consider whether you
have a disorder that satisfies the criteria of a listing in another body system. For
example, we will evaluate hemophilic joint deformity under 101.00; polycythemia vera
under 103.00, 104.00, or 111.00; chronic iron overload resulting from repeated RBC
transfusion (transfusion hemosiderosis) under 103.00, 104.00, or 105.00; and the effects
of intracranial bleeding or stroke under 111.00 or 112.00.
2. If you have a severe medically determinable impairment(s) that does not meet a
listing, we will determine whether your impairment(s) medically equals a listing.
(See section 416.926 of this chapter.) Hematological disorders may be associated with
disorders in other body systems, and we consider the combined effects of multiple
impairments when we determine whether they medically equal a listing. If your impairment(s)
does not medically equal a listing, we will also consider whether it functionally
equals the listings. (See section 416.926a of this chapter.) We use the rules in §416.994a
of this chapter when we decide whether you continue to be disabled.
107.01 Category of Impairments, Hematological Disorders
107.05 Hemolytic anemias, including sickle cell disease, thalassemia, and their variants (see 107.00C), with:
A. Documented painful (vaso-occlusive) crises requiring parenteral (intravenous or intramuscular)
narcotic medication, occurring at least six times within a 12-month period with at
least 30 days between crises.
OR
B. Complications of hemolytic anemia requiring at least three hospitalizations within
a 12-month period and occurring at least 30 days apart. Each hospitalization must
last at least 48 hours, which can include hours in a hospital emergency department
or comprehensive sickle cell disease center immediately before the hospitalization
(see 107.00C2).
OR
C. Hemoglobin measurements of 7.0 grams per deciliter (g/dL) or less, occurring at least
three times within a 12 month period with at least 30 days between measurements.
OR
D. Beta thalassemia major requiring life-long RBC transfusions at least once every 6
weeks to maintain life (see 107.00C4).
107.08 Disorders of thrombosis and hemostasis, including hemophilia and thrombocytopenia (see 107.00D), with complications requiring
at least three hospitalizations within a 12-month period and occurring at least 30
days apart. Each hospitalization must last at least 48 hours, which can include hours
in a hospital emergency department or comprehensive hemophilia treatment center immediately
before the hospitalization (see 107.00D2).
107.10 Disorders of bone marrow failure, including myelodysplastic syndromes, aplastic anemia, granulocytopenia, and myelofibrosis
(see 107.00E), with:
A. Complications of bone marrow failure requiring at least three hospitalizations
within a 12-month period and occurring at least 30 days apart. Each hospitalization
must last at least 48 hours, which can include hours in a hospital emergency department
immediately before the hospitalization (see 107.00E2).
OR
B. Myelodysplastic syndromes or aplastic anemias requiring life-long RBC transfusions
at least once every 6 weeks to maintain life (see 107.00E3).
107.17 Hematological disorders treated by bone marrow or stem cell transplantation (see 107.00F). Consider under a disability for at least 12 consecutive months from
the date of transplantation. After that, evaluate any residual impairment(s) under
the criteria for the affected body system.