Program Operations Manual System (POMS)
TN 1 (10-08)
DI 23022.105 Anaplastic Adrenal Cancer - Adult
COMPASSIONATE ALLOWANCE INFORMATION
ANAPLASTIC ADRENAL CANCER - ADULT
Anaplastic Adrenal Cancer is a sub-type of adrenal cancer which shows virtually no cellular differentiation. It is not associated with overproduction of hormones as is seen in other types of adrenal carcinomas. Abdominal pain is a presenting symptom.
Adrenal Carcinoma, Anaplastic Adrenal Cancer
DIAGNOSTIC TESTING AND CODING
CT and MRI imaging are used in the diagnosis of adrenal lesions, but a biopsy is required for definite diagnosis.
Radical surgical excision is the treatment for individuals with localized malignancies and remains the only method by which long-term disease-free survival may be achieved.
Median survival for anaplastic adrenal cancer is 5 months as compared with a median survival of 40 months for differentiated adrenal cancers.
SUGGESTED PROGRAMMATIC ASSESSMENT*
Suggested MER for Evaluation: Imaging studies of CT scan/MRI will suggest a diagnosis which must be confirmed by biopsy.
Suggested Listings for Evaluation:
Anaplastic carcinoma of the adrenal gland is evaluated under 13.21 A if inoperable, unresectable, or recurrent. Anaplastic cancer of the adrenal glands with metastases is evaluated under 13.21 B.
* Adjudicators may, at their discretion, use the Medical Evidence of Record or Listings suggested to evaluate the claim. However, the decision to allow or deny the claim rests with the adjudicator.
Last Updated: 9/10/08
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